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FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures
In this study, we report that the purified wild-type FANCI (Fanconi anemia complementation group I) protein directly binds to a variety of DNA substrates. The DNA binding domain roughly encompasses residues 200–1000, as suggested by the truncation study. When co-expressed in insect cells, a small fr...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782037/ https://ncbi.nlm.nih.gov/pubmed/19561358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.016006 |
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