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Emerging evidence of a link between the polycystins and the mTOR pathways
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disease characterized by the formation of renal cysts. This disease can be caused by mutations in two genes, PKD1 and PKD2, which encode polycystin-1 (PC-1) and -2 (PC-2), respectively. PC-1 is a large plasma membrane receptor involve...
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| Format: | Artigo |
| Language: | Inglês |
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BioMed Central
2009
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781793/ https://ncbi.nlm.nih.gov/pubmed/19863783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8417-2-6 |
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