Androgen via p21 Inhibits Tumor Necrosis Factor α-induced JNK Activation and Apoptosis

The male hormone androgen is a growth/survival factor for its target tissues or organs. Yet, the underlying mechanism is incompletely understood. Here, we report that androgen via p21 inhibits tumor necrosis factor α-induced JNK activation and apoptosis. Inhibition by androgen requires the transcrip...

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Detalhes bibliográficos
Main Authors: Tang, Fangming, Kokontis, John, Lin, Yuting, Liao, Shutsung, Lin, Anning, Xiang, Jialing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781650/
https://ncbi.nlm.nih.gov/pubmed/19723627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.042994
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