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A Promiscuous Conformational Switch in the Secondary Multidrug Transporter MdfA
Multidrug (Mdr) transporters are membrane proteins that actively export structurally dissimilar drugs from the cell, thereby rendering the cell resistant to toxic compounds. Similar to substrate-specific transporters, Mdr transporters also undergo substrate-induced conformational changes. However, t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781643/ https://ncbi.nlm.nih.gov/pubmed/19808670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050658 |
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