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A Promiscuous Conformational Switch in the Secondary Multidrug Transporter MdfA
Multidrug (Mdr) transporters are membrane proteins that actively export structurally dissimilar drugs from the cell, thereby rendering the cell resistant to toxic compounds. Similar to substrate-specific transporters, Mdr transporters also undergo substrate-induced conformational changes. However, t...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781643/ https://ncbi.nlm.nih.gov/pubmed/19808670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050658 |
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