p63 Suppresses Non-epidermal Lineage Markers in a Bone Morphogenetic Protein-dependent Manner via Repression of Smad7

p63, a p53 family member, plays an essential role in epidermal development by regulating its transcriptional program. Here we report a previously uncovered role of p63 in controlling bone morphogenetic protein (BMP) signaling, which is required for maintaining low expression levels of several non-ep...

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Hlavní autoři: De Rosa, Laura, Antonini, Dario, Ferone, Giustina, Russo, Monia T., Yu, Paul B., Han, Rong, Missero, Caterina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Molecular Basis of Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781612/
https://ncbi.nlm.nih.gov/pubmed/19717565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.049619
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