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The protein kinase p38α destabilizes p63 to limit epidermal stem cell frequency and tumorigenic potential

The molecular circuitry directing tissue development and homeostasis is hardwired by genetic programs but may also be subject to fine-tuning or major modification by environmental conditions. It remains unclear whether such malleability is indeed at work—particularly in tissues directly in contact w...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Choo, Min-Kyung, Kraft, Stefan, Missero, Caterina, Park, Jin Mo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207192/
https://ncbi.nlm.nih.gov/pubmed/30301786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau0727
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