Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition

The multilayered epidermis is established through a stratification program, which is accompanied by a shift from symmetric toward asymmetric divisions (ACD), a process under tight control of the transcription factor p63. However, the physiological signals regulating p63 activity in epidermal morphog...

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Huvudupphovsmän: Günschmann, Christian, Stachelscheid, Heike, Akyüz, Mehmet Deniz, Schmitz, Annika, Missero, Caterina, Brüning, Jens C., Niessen, Carien M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730059/
https://ncbi.nlm.nih.gov/pubmed/23906066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.05.017
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