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Involvement of Ionizable Groups in Catalysis of Human Liver Glycolate Oxidase
Glycolate oxidase is a flavin-dependent, peroxisomal enzyme that oxidizes α-hydroxy acids to the corresponding α-keto acids, with reduction of oxygen to H(2)O(2). In plants, the enzyme participates in photorespiration. In humans, it is a potential drug target for treatment of primary hyperoxaluria,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781520/ https://ncbi.nlm.nih.gov/pubmed/19758989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.040063 |
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