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Substrate Orientation and Catalysis at the Molybdenum Site in Xanthine Oxidase: CRYSTAL STRUCTURES IN COMPLEX WITH XANTHINE AND LUMAZINE

Xanthine oxidoreductase is a ubiquitous cytoplasmic protein that catalyzes the final two steps in purine catabolism. We have previously investigated the catalytic mechanism of the enzyme by rapid reaction kinetics and x-ray crystallography using the poor substrate 2-hydroxy-6-methylpurine, focusing...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Pauff, James M., Cao, Hongnan, Hille, Russ
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659234/
https://ncbi.nlm.nih.gov/pubmed/19109252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804517200
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