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mTORβ Splicing Isoform Promotes Cell Proliferation and Tumorigenesis
The mTOR (mammalian target of rapamycin) promotes growth in response to nutrients and growth factors and is deregulated in numerous pathologies, including cancer. The mechanisms by which mTOR senses and regulates energy metabolism and cell growth are relatively well understood, whereas the molecular...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781479/ https://ncbi.nlm.nih.gov/pubmed/19726679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056085 |
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