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mTORβ Splicing Isoform Promotes Cell Proliferation and Tumorigenesis

The mTOR (mammalian target of rapamycin) promotes growth in response to nutrients and growth factors and is deregulated in numerous pathologies, including cancer. The mechanisms by which mTOR senses and regulates energy metabolism and cell growth are relatively well understood, whereas the molecular...

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書誌詳細
主要な著者: Panasyuk, Ganna, Nemazanyy, Ivan, Zhyvoloup, Aleksander, Filonenko, Valeriy, Davies, Derek, Robson, Mathew, Pedley, R. Barbara, Waterfield, Michael, Gout, Ivan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781479/
https://ncbi.nlm.nih.gov/pubmed/19726679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056085
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