mTORβ Splicing Isoform Promotes Cell Proliferation and Tumorigenesis

The mTOR (mammalian target of rapamycin) promotes growth in response to nutrients and growth factors and is deregulated in numerous pathologies, including cancer. The mechanisms by which mTOR senses and regulates energy metabolism and cell growth are relatively well understood, whereas the molecular...

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Detalhes bibliográficos
Main Authors: Panasyuk, Ganna, Nemazanyy, Ivan, Zhyvoloup, Aleksander, Filonenko, Valeriy, Davies, Derek, Robson, Mathew, Pedley, R. Barbara, Waterfield, Michael, Gout, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781479/
https://ncbi.nlm.nih.gov/pubmed/19726679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056085
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