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mTORβ Splicing Isoform Promotes Cell Proliferation and Tumorigenesis
The mTOR (mammalian target of rapamycin) promotes growth in response to nutrients and growth factors and is deregulated in numerous pathologies, including cancer. The mechanisms by which mTOR senses and regulates energy metabolism and cell growth are relatively well understood, whereas the molecular...
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| Main Authors: | , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Biochemistry and Molecular Biology
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781479/ https://ncbi.nlm.nih.gov/pubmed/19726679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056085 |
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