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mTORβ Splicing Isoform Promotes Cell Proliferation and Tumorigenesis

The mTOR (mammalian target of rapamycin) promotes growth in response to nutrients and growth factors and is deregulated in numerous pathologies, including cancer. The mechanisms by which mTOR senses and regulates energy metabolism and cell growth are relatively well understood, whereas the molecular...

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Sonraí Bibleagrafaíochta
Main Authors: Panasyuk, Ganna, Nemazanyy, Ivan, Zhyvoloup, Aleksander, Filonenko, Valeriy, Davies, Derek, Robson, Mathew, Pedley, R. Barbara, Waterfield, Michael, Gout, Ivan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781479/
https://ncbi.nlm.nih.gov/pubmed/19726679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.056085
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