Heparan Sulfate Proteoglycan Modulation of Wnt5A Signal Transduction in Metastatic Melanoma Cells

Heparan sulfate proteoglycans (HSPGs) are important modulators for optimizing signal transduction of many pathways, including the Wnt pathways. We demonstrate that HSPG glycosaminoglycan levels increased with increasing metastatic potential of melanoma cells. Previous studies have demonstrated that...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: O'Connell, Michael P., Fiori, Jennifer L., Kershner, Emily K., Frank, Brittany P., Indig, Fred E., Taub, Dennis D., Hoek, Keith S., Weeraratna, Ashani T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2009
विषय:
Glycobiology and Extracellular Matrices
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781415/
https://ncbi.nlm.nih.gov/pubmed/19696445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.028498
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