Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase

Hemorrhagic shock (HS) and resuscitation leads to widespread production of oxidant species. Activation of the enzyme poly(ADP-ribose) polymerase (PARP) has been shown to contribute to cell necrosis and organ failure in various disease conditions associated with oxidative stress. We tested the hypoth...

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Main Authors: Liaudet, Lucas, Soriano, Francisco Garcia, Szabó, Éva, Virág, László, Mabley, Jon G., Salzman, Andrew L., Szabó, Csaba
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC27808/
https://ncbi.nlm.nih.gov/pubmed/10954738
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