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Novel, Potent and Radio-Iodinatable Somatostatin Receptor 1 (sst(1)) Selective Analogues

The proposed sst(1) pharmacophore1 derived from the NMR structures of a family of mono- and dicyclic undecamers was used to design octa-, hepta- and hexamers with high affinity and selectivity for the somatostatin sst(1) receptor. These compounds were tested for their in vitro binding properties to...

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Autors principals: Erchegyi, Judit, Cescato, Renzo, Grace, Christy Rani R., Waser, Beatrice, Piccand, Véronique, Hoyer, Daniel, Riek, Roland, Rivier, Jean E., Reubi, Jean Claude
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779710/
https://ncbi.nlm.nih.gov/pubmed/19351180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801314f
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