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Novel sst(2)-selective somatostatin agonists. Three-dimensional consensus structure by NMR

The three-dimensional NMR structures of six octapeptide agonist analogues of somatostatin (SRIF) in the free form are described. These analogues, with the basic sequence H-DPhe/Phe(2)-c[Cys(3)-Xxx(7)-DTrp(8)-Lys(9)-Thr(10)-Cys(14)]-Thr-NH(2) (the numbering refers to the position in native SRIF), wit...

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Autors principals: Grace, Christy Rani R., Erchegyi, Judit, Koerber, Steven C., Reubi, Jean Claude, Rivier, Jean, Riek, Roland
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515173/
https://ncbi.nlm.nih.gov/pubmed/16854054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060363v
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