טוען...

Domain Requirements and Sequence Specificity of DNA Binding for the Forkhead Transcription Factor FOXP3

The forkhead, winged-helix transcription factor FOXP3 is preferentially expressed in T regulatory (Treg) cells and is critical for their immunosuppressive function. Mutations that abolish FOXP3 function lead to systemic autoimmunity in mice and humans. However, the manner by which FOXP3 recognizes c...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Koh, Kian Peng, Sundrud, Mark S., Rao, Anjana
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779587/
https://ncbi.nlm.nih.gov/pubmed/19956618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008109
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!