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Domain Requirements and Sequence Specificity of DNA Binding for the Forkhead Transcription Factor FOXP3

The forkhead, winged-helix transcription factor FOXP3 is preferentially expressed in T regulatory (Treg) cells and is critical for their immunosuppressive function. Mutations that abolish FOXP3 function lead to systemic autoimmunity in mice and humans. However, the manner by which FOXP3 recognizes c...

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Bibliografski detalji
Glavni autori: Koh, Kian Peng, Sundrud, Mark S., Rao, Anjana
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779587/
https://ncbi.nlm.nih.gov/pubmed/19956618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008109
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