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DNA-binding specificity changes in the evolution of forkhead transcription factors

The evolution of transcriptional regulatory networks entails the expansion and diversification of transcription factor (TF) families. The forkhead family of TFs, defined by a highly conserved winged helix DNA-binding domain (DBD), has diverged into dozens of subfamilies in animals, fungi, and relate...

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Autori principali: Nakagawa, So, Gisselbrecht, Stephen S., Rogers, Julia M., Hartl, Daniel L., Bulyk, Martha L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725104/
https://ncbi.nlm.nih.gov/pubmed/23836653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310430110
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