Integrated requirement of non‐specific and sequence‐specific DNA binding in Myc‐driven transcription

Eukaryotic transcription factors recognize specific DNA sequence motifs, but are also endowed with generic, non‐specific DNA‐binding activity. How these binding modes are integrated to determine select transcriptional outputs remains unresolved. We addressed this question by site‐directed mutagenesi...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Pellanda, Paola, Dalsass, Mattia, Filipuzzi, Marco, Loffreda, Alessia, Verrecchia, Alessandro, Castillo Cano, Virginia, Thabussot, Hugo, Doni, Mirko, Morelli, Marco J, Soucek, Laura, Kress, Theresia, Mazza, Davide, Mapelli, Marina, Beaulieu, Marie‐Eve, Amati, Bruno, Sabò, Arianna
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126922/
https://ncbi.nlm.nih.gov/pubmed/33792944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105464
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