Integrated requirement of non‐specific and sequence‐specific DNA binding in Myc‐driven transcription

Eukaryotic transcription factors recognize specific DNA sequence motifs, but are also endowed with generic, non‐specific DNA‐binding activity. How these binding modes are integrated to determine select transcriptional outputs remains unresolved. We addressed this question by site‐directed mutagenesi...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Pellanda, Paola, Dalsass, Mattia, Filipuzzi, Marco, Loffreda, Alessia, Verrecchia, Alessandro, Castillo Cano, Virginia, Thabussot, Hugo, Doni, Mirko, Morelli, Marco J, Soucek, Laura, Kress, Theresia, Mazza, Davide, Mapelli, Marina, Beaulieu, Marie‐Eve, Amati, Bruno, Sabò, Arianna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126922/
https://ncbi.nlm.nih.gov/pubmed/33792944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105464
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