Integrated requirement of non‐specific and sequence‐specific DNA binding in Myc‐driven transcription

Eukaryotic transcription factors recognize specific DNA sequence motifs, but are also endowed with generic, non‐specific DNA‐binding activity. How these binding modes are integrated to determine select transcriptional outputs remains unresolved. We addressed this question by site‐directed mutagenesi...

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Publicat a:EMBO J
Autors principals: Pellanda, Paola, Dalsass, Mattia, Filipuzzi, Marco, Loffreda, Alessia, Verrecchia, Alessandro, Castillo Cano, Virginia, Thabussot, Hugo, Doni, Mirko, Morelli, Marco J, Soucek, Laura, Kress, Theresia, Mazza, Davide, Mapelli, Marina, Beaulieu, Marie‐Eve, Amati, Bruno, Sabò, Arianna
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126922/
https://ncbi.nlm.nih.gov/pubmed/33792944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105464
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