Circulating TGFβ in Marfan's Syndrome

BACKGROUND: Marfan syndrome (MFS) is caused by mutations in the fibrillin-1 gene and dysregulation of transforming growth factor β (TGFβ). Recent evidence suggests that losartan, an AT1 blocker that blunts TGFβ activation, may be an effective treatment for MFS. We hypothesized that dysregulation of...

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Main Authors: Matt, Peter, Schoenhoff, Florian, Habashi, Jennifer, Holm, Tammy, Van Erp, Christel, Loch, David, Carlson, Olga D., Griswold, Benjamin F., Fu, Qin, De Backer, Julie, Loeys, Bart, Huso, David, McDonnell, Nazli B., Van Eyk, Jennifer E., Dietz, Harry C.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779568/
https://ncbi.nlm.nih.gov/pubmed/19635970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.841981
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