Circulating TGFβ in Marfan's Syndrome

BACKGROUND: Marfan syndrome (MFS) is caused by mutations in the fibrillin-1 gene and dysregulation of transforming growth factor β (TGFβ). Recent evidence suggests that losartan, an AT1 blocker that blunts TGFβ activation, may be an effective treatment for MFS. We hypothesized that dysregulation of...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Matt, Peter, Schoenhoff, Florian, Habashi, Jennifer, Holm, Tammy, Van Erp, Christel, Loch, David, Carlson, Olga D., Griswold, Benjamin F., Fu, Qin, De Backer, Julie, Loeys, Bart, Huso, David, McDonnell, Nazli B., Van Eyk, Jennifer E., Dietz, Harry C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779568/
https://ncbi.nlm.nih.gov/pubmed/19635970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.841981
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