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The CEACAM1 N-terminal Ig domain mediates cis- and trans-binding and is essential for allosteric rearrangements of CEACAM1 microclusters

Cell adhesion molecules (CAMs) sense the extracellular microenvironment and transmit signals to the intracellular compartment. In this investigation, we addressed the mechanism of signal generation by ectodomains of single-pass transmembrane homophilic CAMs. We analyzed the structure and homophilic...

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Detaylı Bibliyografya
Asıl Yazarlar: Klaile, Esther, Vorontsova, Olga, Sigmundsson, Kristmundur, Müller, Mario M., Singer, Bernhard B., Öfverstedt, Lars-Göran, Svensson, Stina, Skoglund, Ulf, Öbrink, Björn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779236/
https://ncbi.nlm.nih.gov/pubmed/19948502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904149
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