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Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src

Carcinoembryonic antigen (CEA)–related cell adhesion molecule 1 (CAM1 [CEACAM1]) mediates homophilic cell adhesion and regulates signaling. Although there is evidence that CEACAM1 binds and activates SHP-1, SHP-2, and c-Src, knowledge about the mechanism of transmembrane signaling is lacking. To ana...

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書誌詳細
主要な著者: Müller, Mario M., Klaile, Esther, Vorontsova, Olga, Singer, Bernhard B., Öbrink, Björn
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779222/
https://ncbi.nlm.nih.gov/pubmed/19948503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904150
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