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Highly stable trypsin-aggregate coatings on polymer nanofibers for repeated protein digestion

A stable and robust trypsin-based biocatalytic system was developed and demonstrated for proteomic applications. The system utilizes polymer nanofibers coated with trypsin aggregates for immobilized protease digestions. After covalently attaching an initial layer of trypsin to the polymer nanofibers...

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Detalhes bibliográficos
Main Authors: Kim, Byoung Chan, Lopez-Ferrer, Daniel, Lee, Sang-Mok, Ahn, Hye-Kyung, Nair, Sujith, Kim, Seong H., Kim, Beom Soo, Petritis, Konstantinos, Camp, David G., Grate, Jay W., Smith, Richard D., Koo, Yoon-Mo, Gu, Man Bock, Kim, Jungbae
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779140/
https://ncbi.nlm.nih.gov/pubmed/19288524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800591
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