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Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins

At least 17 members of the protein disulphide isomerase (PDI) family of oxidoreductases are present in the endoplasmic reticulum (ER) of mammalian cells. They are thought to catalyse disulphide formation to aid folding or to regulate protein function; however, little is known about their individual...

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Detalhes bibliográficos
Main Authors: Jessop, Catherine E., Watkins, Rachel H., Simmons, Jennifer J., Tasab, Mohammed, Bulleid, Neil J.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779130/
https://ncbi.nlm.nih.gov/pubmed/19887585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.059154
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