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Life and Death of a BiP Substrate

BiP is the mammalian endoplasmic reticulum (ER) Hsp70 orthologue that plays a major role in all functions of this organelle including the seemingly opposing functions of aiding the maturation of unfolded nascent proteins and identifying and targeting chronically unfolded proteins for degradation. Th...

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Autors principals: Otero, Joel H., Lizák, Beáta, Hendershot, Linda M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883687/
https://ncbi.nlm.nih.gov/pubmed/20026282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2009.12.008
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