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Characterization of an ERAD pathway for non-glycosylated BiP substrates which requires Herp
To investigate the disposal of non-glycosylated BiP substrates, we used a non-secreted κ LC, which exists in a partially (ox1) and completely (ox2) oxidized state. The ox2 form is partially reduced in order to be degraded and only the ox1 form is ubiquitinated and associates with both Herp, and Derl...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2149893/ https://ncbi.nlm.nih.gov/pubmed/18042451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.09.012 |
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