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Sil1, a nucleotide exchange factor for BiP, is not required for antibody assembly or secretion

Sil1 is a nucleotide exchange factor for the endoplasmic reticulum chaperone BiP, and mutations in this gene lead to Marinesco–Sjögren syndrome (MSS), a debilitating autosomal recessive disease characterized by multisystem defects. A mouse model for MSS was previously produced by disrupting Sil1 usi...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Ichhaporia, Viraj P., Sanford, Tyler, Howes, Jenny, Marion, Tony N., Hendershot, Linda M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310734/
https://ncbi.nlm.nih.gov/pubmed/25473114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-09-1392
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