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Sil1, a nucleotide exchange factor for BiP, is not required for antibody assembly or secretion
Sil1 is a nucleotide exchange factor for the endoplasmic reticulum chaperone BiP, and mutations in this gene lead to Marinesco–Sjögren syndrome (MSS), a debilitating autosomal recessive disease characterized by multisystem defects. A mouse model for MSS was previously produced by disrupting Sil1 usi...
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| 發表在: | Mol Biol Cell |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Cell Biology
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310734/ https://ncbi.nlm.nih.gov/pubmed/25473114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-09-1392 |
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