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Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids

Any protein synthesized in the secretory pathway has the potential to misfold and would need to be recognized and ubiquitylated for degradation. This is astounding since only a few ERAD-specific E3 ligases have been identified. To begin to understand substrate recognition, we wished to map the ubiqu...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Shimizu, Yuichiro, Okuda-Shimizu, Yuki, Hendershot, Linda M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031134/
https://ncbi.nlm.nih.gov/pubmed/21172657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.033
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