One-pot Synthesis of Lactams Using Domino Reactions: Combination of Schmidt Reaction with Sakurai and Aldol Reactions

[Image: see text] A series of domino reactions in which the intramolecular Schmidt reaction is combined with either a Sakurai reaction, an aldol reaction, or both is reported. The Sakurai reaction of an allylsilane with an azido-containing enone under Lewis acidic conditions followed by protonation...

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Bibliographic Details
Main Authors: Huh, Chan Woo, Somal, Gagandeep K., Katz, Christopher E., Pei, Huaxing, Zeng, Yibin, Douglas, Justin T., Aubé, Jeffrey
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778731/
https://ncbi.nlm.nih.gov/pubmed/19761271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo901843w
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