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Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help
The CD8(+) cytotoxic T cell response to pathogens is thought to be CD4(+) helper T cell independent because infectious agents provide their own inflammatory signals. Mice that lack CD4(+) T cells mount a primary CD8 response to Listeria monocytogenes equal to that of wild-type mice and rapidly clear...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778341/ https://ncbi.nlm.nih.gov/pubmed/12690202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1083317 |
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