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Defining the DNA Substrate Binding Sites on HIV-1 Integrase

A tetramer model for HIV-1 IN with DNA representing the LTR termini was previously assembled to predict the IN residues that interact with the LTR termini; these predictions were experimentally verified for nine amino acid residues (Chen et al, J. Biol. Chem. 281, 4173-4182 (2006)). In a similar str...

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Detalhes bibliográficos
Main Authors: Dolan, James, Chen, Aiping, Weber, Irene T., Harrison, Robert W., Leis, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778331/
https://ncbi.nlm.nih.gov/pubmed/19014951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.083
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