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Efficient Oncogene Silencing and Metastasis Inhibition via Systemic Delivery of siRNA
The selective delivery of small interfering RNA (siRNA) to metastatic tumors remains a challenging task. We have developed a nanoparticle (NP) formulation composed of siRNA, a carrier DNA, a polycationic peptide, and cationic liposomes. The NP was obtained by a self-assembling process, followed by s...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2778045/ https://ncbi.nlm.nih.gov/pubmed/18388916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.51 |
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