MODULATION OF THE BCL-2 FAMILY BLOCKS SEPSIS-INDUCED DEPLETION OF DENDRITIC CELLS AND MACROPHAGES

This study examined the fate of dendritic cells (DCs) and macrophages (MΦ) in vivo in a murine model of sepsis. Wild-type, knockout, and transgenic mice were used to examine the role of Bcl-2 family members on the regulation of splenic DCs and MΦ survival. Bim knockout (Bim(−/−)) mice and mice overe...

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Hlavní autoři: Peck-Palmer, Octavia M., Unsinger, Jacqueline, Chang, Katherine C., McDonough, Jacquelyn S., Perlman, Harris, McDunn, Jonathan E., Hotchkiss, Richard S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778022/
https://ncbi.nlm.nih.gov/pubmed/18838943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31818ba2a2
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