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Anti-angiogenic and anti-tumor activity of AEAC, a novel small molecule inhibitor of thymidine phosphorylase, in combination with the VEGF-Trap
PURPOSE: Tumors produce multiple pro-angiogenic factors, making it unlikely that agents targeting a single angiogenic pathway will be sufficient to treat the spectrum of tumors which occur clinically. PD-ECGF (platelet-derived endothelial cell growth factor) has angiogenic activity in vitro and in v...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777687/ https://ncbi.nlm.nih.gov/pubmed/19671868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3203 |
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