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Thymidine phosphorylase is angiogenic and promotes tumor growth.

Platelet-derived endothelial cell growth factor was previously identified as the sole angiogenic activity present in platelets; it is now known to be thymidine phosphorylase (TP). The effect of TP on [methyl-3H]thymidine uptake does not arise from de novo DNA synthesis and the molecule is not a grow...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Moghaddam, A, Zhang, H T, Fan, T P, Hu, D E, Lees, V C, Turley, H, Fox, S B, Gatter, K C, Harris, A L, Bicknell, R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42624/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7532308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.4.998
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