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Dynamic Conformational Responses of a Human Cannabinoid Receptor-1 Helix Domain to Its Membrane Environment

The influence of membrane environment on human cannabinoid 1 (hCB(1)) receptor transmembrane helix (TMH) conformational dynamics was investigated by solid-state NMR and site-directed spin labeling/EPR with a synthetic peptide, hCB(1)(T377-E416), corresponding to the receptor’s C-terminal component,...

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Main Authors: Tiburu, Elvis K., Gulla, Stefano V., Tiburu, Mark, Janero, David R., Budil, David E., Makriyannis, Alexandros
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777635/
https://ncbi.nlm.nih.gov/pubmed/19485422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802235w
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