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Malic enzyme is present in mouse islets and modulates insulin secretion
AIMS/HYPOTHESIS: The pyruvate-malate shuttle is a metabolic cycle in pancreatic beta-cells and important for beta-cell function. Cytosolic malic enzyme (ME) carries out an essential step in the shuttle by converting malate to pyruvate and generating NADPH. In rat islets the pyruvate-malate shuttle m...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777632/ https://ncbi.nlm.nih.gov/pubmed/18802677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1155-0 |
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