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The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta-cells

AIMS/HYPOTHESIS: Pyruvate carboxylase (PC) or pyruvate dehydrogenase (PDH) is required to transfer carbons from pyruvate into the Krebs cycle. PC activity is preserved in the islets of obese animals but it is reduced in the islets of type 2 diabetic animals, suggesting that PC is important in beta-c...

詳細記述

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書誌詳細
主要な著者: Xu, Jianxiang, Han, Junying, Long, Yun Shi, Epstein, Paul N., Liu, Ye Qi
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777625/
https://ncbi.nlm.nih.gov/pubmed/18769905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1130-9
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