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The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta-cells
AIMS/HYPOTHESIS: Pyruvate carboxylase (PC) or pyruvate dehydrogenase (PDH) is required to transfer carbons from pyruvate into the Krebs cycle. PC activity is preserved in the islets of obese animals but it is reduced in the islets of type 2 diabetic animals, suggesting that PC is important in beta-c...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777625/ https://ncbi.nlm.nih.gov/pubmed/18769905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1130-9 |
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