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GroEL/GroES cycling: ATP binds to an open ring before substrate protein favoring protein binding and production of the native state
The GroEL/GroES reaction cycle involves steps of ATP and polypeptide binding to an open GroEL ring before the GroES encapsulation step that triggers productive folding in a sequestered chamber. The physiological order of addition of ATP and nonnative polypeptide, typically to the open trans ring of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777187/ https://ncbi.nlm.nih.gov/pubmed/19915138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911556106 |
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