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Structures of BIR domains from human NAIP and cIAP2

The inhibitor of apoptosis (IAP) family of proteins contains key modulators of apoptosis and inflammation that interact with caspases through baculovirus IAP-repeat (BIR) domains. Overexpression of IAP proteins frequently occurs in cancer cells, thus counteracting the activated apoptotic program. Th...

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Bibliografiset tiedot
Päätekijät: Herman, Maria Dolores, Moche, Martin, Flodin, Susanne, Welin, Martin, Trésaugues, Lionel, Johansson, Ida, Nilsson, Martina, Nordlund, Pär, Nyman, Tomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Union of Crystallography 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777033/
https://ncbi.nlm.nih.gov/pubmed/19923725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109038597
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