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Structures of BIR domains from human NAIP and cIAP2

The inhibitor of apoptosis (IAP) family of proteins contains key modulators of apoptosis and inflammation that interact with caspases through baculovirus IAP-repeat (BIR) domains. Overexpression of IAP proteins frequently occurs in cancer cells, thus counteracting the activated apoptotic program. Th...

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Detaylı Bibliyografya
Asıl Yazarlar: Herman, Maria Dolores, Moche, Martin, Flodin, Susanne, Welin, Martin, Trésaugues, Lionel, Johansson, Ida, Nilsson, Martina, Nordlund, Pär, Nyman, Tomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2009
Konular:
Structural Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777033/
https://ncbi.nlm.nih.gov/pubmed/19923725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109038597
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