Structures of BIR domains from human NAIP and cIAP2

The inhibitor of apoptosis (IAP) family of proteins contains key modulators of apoptosis and inflammation that interact with caspases through baculovirus IAP-repeat (BIR) domains. Overexpression of IAP proteins frequently occurs in cancer cells, thus counteracting the activated apoptotic program. Th...

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Detalhes bibliográficos
Main Authors: Herman, Maria Dolores, Moche, Martin, Flodin, Susanne, Welin, Martin, Trésaugues, Lionel, Johansson, Ida, Nilsson, Martina, Nordlund, Pär, Nyman, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Structural Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777033/
https://ncbi.nlm.nih.gov/pubmed/19923725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109038597
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