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Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains

Toll-like receptors (TLRs) play a key role in the innate immune system. The TLR7, 8, and 9 compose a family of intracellularly localized TLRs that signal in response to pathogen-derived nucleic acids. So far, there are no crystallographic structures for TLR7, 8, and 9. For this reason, their ligand-...

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書誌詳細
主要な著者: Wei, Tiandi, Gong, Jing, Jamitzky, Ferdinand, Heckl, Wolfgang M, Stark, Robert W, Rössle, Shaila C
フォーマット: Artigo
言語:Inglês
出版事項: Wiley Subscription Services, Inc., A Wiley Company 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776956/
https://ncbi.nlm.nih.gov/pubmed/19521997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.186
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