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Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains
Toll-like receptors (TLRs) play a key role in the innate immune system. The TLR7, 8, and 9 compose a family of intracellularly localized TLRs that signal in response to pathogen-derived nucleic acids. So far, there are no crystallographic structures for TLR7, 8, and 9. For this reason, their ligand-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776956/ https://ncbi.nlm.nih.gov/pubmed/19521997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.186 |
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