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NMR-based characterization of a refolding intermediate of β2-microglobulin labeled using a wheat germ cell-free system
In patients with dialysis-related amyloidosis, β2-microglobulin (β2-m) is a major structural component of amyloid fibrils. It has been suggested that the partial unfolding of β2-m is a prerequisite to the formation of amyloid fibrils, and that the folding intermediate trapped by the non-native trans...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776947/ https://ncbi.nlm.nih.gov/pubmed/19606503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.179 |
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