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3D structure of amyloid protofilaments of β(2)-microglobulin fragment probed by solid-state NMR

Understanding the structure and formation of amyloid fibrils, the filamentous aggregates of proteins and peptides, is crucial in preventing diseases caused by their deposition and, moreover, for obtaining further insight into the mechanism of protein folding and misfolding. We have combined solid-st...

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Hlavní autoři: Iwata, Kentaro, Fujiwara, Toshimichi, Matsuki, Yoh, Akutsu, Hideo, Takahashi, Satoshi, Naiki, Hironobu, Goto, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838716/
https://ncbi.nlm.nih.gov/pubmed/17108084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607180103
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