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Hepatic drug transporters and nuclear receptors: Regulation by therapeutic agents
The canalicular membrane represents the excretory pole of hepatocytes. Bile is an important route of elimination of potentially toxic endo- and xenobiotics (including drugs and toxins), mediated by the major canalicular transporters: multidrug resistance protein 1 (MDR1, ABCB1), also known as P-glyc...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The WJG Press and Baishideng
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776836/ https://ncbi.nlm.nih.gov/pubmed/19084913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.7068 |
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