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Hepatic drug transporters and nuclear receptors: Regulation by therapeutic agents

The canalicular membrane represents the excretory pole of hepatocytes. Bile is an important route of elimination of potentially toxic endo- and xenobiotics (including drugs and toxins), mediated by the major canalicular transporters: multidrug resistance protein 1 (MDR1, ABCB1), also known as P-glyc...

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Hlavní autoři: Mottino, Aldo D, Catania, Viviana A
Médium: Artigo
Jazyk:Inglês
Vydáno: The WJG Press and Baishideng 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776836/
https://ncbi.nlm.nih.gov/pubmed/19084913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.7068
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