Sdhd and Sdhd/H19 Knockout Mice Do Not Develop Paraganglioma or Pheochromocytoma

BACKGROUND: Mitochondrial succinate dehydrogenase (SDH) is a component of both the tricarboxylic acid cycle and the electron transport chain. Mutations of SDHD, the first protein of intermediary metabolism shown to be involved in tumorigenesis, lead to the human tumors paraganglioma (PGL) and pheoch...

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Detalhes bibliográficos
Main Authors: Bayley, Jean-Pierre, van Minderhout, Ivonne, Hogendoorn, Pancras C. W., Cornelisse, Cees J., van der Wal, Annemieke, Prins, Frans A., Teppema, Luc, Dahan, Albert, Devilee, Peter, Taschner, Peter E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776493/
https://ncbi.nlm.nih.gov/pubmed/19956719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007987
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