Similar gene expression profiles of sporadic, PGL2-, and SDHD-linked paragangliomas suggest a common pathway to tumorigenesis

BACKGROUND: Paragangliomas of the head and neck are highly vascular and usually clinically benign tumors arising in the paraganglia of the autonomic nervous system. A significant number of cases (10–50%) are proven to be familial. Multiple genes encoding subunits of the mitochondrial succinate-dehyd...

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Detalhes bibliográficos
Main Authors: Hensen, Erik F, Goeman, Jelle J, Oosting, Jan, Van der Mey, Andel GL, Hogendoorn, Pancras CW, Cremers, Cor WRJ, Devilee, Peter, Cornelisse, Cees J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694828/
https://ncbi.nlm.nih.gov/pubmed/19432956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-25
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